Yes, 1/4" wall is more "beef" than you really need. The front crossmember is fairly short and therefore very rigid, so it's not prone to flexing. Some on this site insist on 3/16" wall tubing, others are satisfied with 1/8" wall thickness. If you are planning on using a heavy, torque-monster engine like a Hemi or a blown big-block, the 3/16 wall would be advisable. Otherwise, it's a matter of preference. Over the last 40+ years I have built over 20 complete frames including several T-buckets, some C-cab deliveries, an Anglia, at least a half-dozen Model-As, a '37 Chevy, and the Deuce replica under my coupe. All but one of the C-cabs were built from 1/8" wall material.
In this case, no torque monster...just the opposite. It's going to be a GM 60 degree V6...please don't hurt yourself laughing. This is going to be a casual cruiser, not a ground shaker.
I had planned on 3/16 wall for the frame rails, just as a matter of playing it safe...now I'm starting to think maybe 1/8" may be the way to go, especially considering I'm planning on a shorter than typical 96" wheelbase. Based on the weight of a 20' section of 3x2, it would save 34 lbs. Hmmmm.
1/8" would be fine for that little V-6, but when you win the lottery and get that blown 454 to drop in there, then what. There is not much difference in the cost of a length of steel.
They use 1/8" wall in drag cars, but they have a full cage with lots of triangles to help support all of it.
Jim is right, 1/8 is really more than sufficient. I only use 3/16 because we tend to overbuild everything, and the 3/16 wall also gives a little more thicknes so you can tap threads into it for non structural things like line clamps, etc. 1/4 would be way overkill IMO, but the car sure would sit nice and low.
Don
Don