Well, its hard to beat a couple of well setup holleys on top of a blower, and there are some carb. mfg.'ers that are resistant to the seperation of the crap E85 thats forced on us. Now, that being said, I love the carbs and have done them long enough to know how to tune them.
HOWEVER, EFI systems are both proven on the street, can be had in kit form for either tunnel rams/blowers/turbos. Ethanol, if you have the tuning capabilities within your efi/ign. system, more power/torque can be had without washing out your rings, wear in your bores/bearings, you can actually make more power. The offset of this though.....your car will start faster, going up and down hills/ altitude won't affect the EFIs, and after they've learned the habits of your engine, will only use as much fuel as needed, no more.
You can outfit a roots blower with a twin throttlebody efi kit, for about $2000-2500 range. If you already have a blower, looking to replace your carbs, its a win/win situation....with the right ign. curve, blower ratio, and a efi, your engine will run cooler, idle better, make more power, and let your engine last longer....
I love carbs, but this crap gas is gonna get worse, plus folks are trying to outlaw our internal combustion engines, the EFIs do a great job of injesting the mess with little distress, and IF tuned correctly, will put out maximum power....